Improved Performance When Using HFIP
• Optimized separation range delivers high performance with no artifacts • Highly durable packing prolongs column lifetime • Low operating pressure reduces system wear and unnecessary downtimes Hexafluoroisopropanol (HFIP) is used as a solvent in GPC for the analysis of important industrial polymers such as polyesters, polyamides and polylactide/glycolide copolymers. For greatly improved performance in extremely polar solvents such as HFIP and trifluoroethanol, we have developed novel “multipore” technology to produce PL HFIPgel, a PS/DVB packing featuring a monodisperse particle size, high pore volume and high resolution. Using PL HFIPgel avoids issues associated with conventional packing and HFIP, such as excessive curvature of calibration curves, dislocations/shoulders on peaks for polydisperse samples and poor resolution in the low MW region. Column efficiency is guaranteed >30,000 p/m and the columns are very durable, with a maximum operating pressure of 145 bar (2030 psi). They are packed and tested in methanol but shipped ready to use in HFIP. PL HFIPgel columns with 7.5 mm ID normally operate at 1 mL/min. However, the 4.6 mm ID columns run at 0.3 mL/min, providing a 70% reduction in solvent consumption with consequent savings in the cost of buying and disposing of solvents.
Columns: Eluent: Flow Rate: Temp: Detector: 2 x PL HFIPgel, 300 x 7.5 mm HFIP + 20mM NaTFAc 1.0 mL/min 40 °C PL-GPC 50 Plus (RI)
Typical Applications Polyesters, polyamides, polylactide/glycolide copolymers
PL HFIPgel Columns Description PL HFIPgel, 250 x 4.6 mm PL HFIPgel, 300 x 7.5 mm PL HFIPgel Guard, 50 x 7.5 mm PL HFIPgel Guard, 50 x 4.6 mm Part No. PL1514-5900HFIP PL1114-6900HFIP PL1114-1900HFIP PL1514-1900HFIP
See Also • Polymer Calibration Standards, with highly characterized molecular weights, page 316
For more information, please visit www.varianinc.com/pl_hfip_gel.html or visit www.varianinc.com/products.html to place an order.