Bond elut™ Cartridge Spe
Bond Elut DEA: Medium Polarity Sorbent
• More polar than C8 but less polar than C2 or CN • Lower ionic capacity than NH2 • Alkyl side chains confer moderately non-polar chracteristics Bond Elut DEA bears some resemblance to Bond Elut NH2 in its Typical Applications Water, biological fluids, non-polar extracts
properties but with a slightly lower capacity as an anion exchange sorbent. DEA has a moderately non-polar character due to the alkyl side chains on the amino functionality. These groups still afford a medium level of polarity, higher than C8 but less polar than C2 or CN-E. Bond Elut DEA is an excellent phase for the extraction of bisphosphonates from human serum and urine. Bisphosphonates are extremely hydrophilic and structurally similar to many endogenous phosphorylated compounds, making their selective extraction from serum or urine very challenging. The unique chemistry of Bond Elut DEA offers excellent selectivity of this class of compounds.
Characteristics Primary retention mechanism Weak anion exchange (aqueous matrix) or polar (non-polar organic matrix) Diethylaminopropyl No Packed bed 8.5 500 40 and 120, irregular 60
Bonded functional group, base material Endcapped Format Typical carbon loading (%) Surface area (m2/g) Particle size (µm), shape Mean pore size (Å)
Bond Elut LRC cartridges (50/box) Sorbent Mass (mg) 100 500 Volume (mL) 10 10 10 10 Bond Elut straight barrel cartridges Sorbent Mass (mg) 50 100 500 Volume (mL) 1 1 1 1 3 3 Particle Size (μm) 40 120 40 120 40 120 Quantity (box) 100 100 100 100 50 50 Part No. 12102078 14102078 12102016 14102016 12102043 14102043 Particle Size (μm) 40 120 40 120 Part No. 12113016 14113016 12113042 14113042
See also • Bond Elut C2, low carbon load non-polar sorbent, page 27 • Bond Elut CN-E, unique selectivity for very non-polar compounds, page 33 36
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